You could ask your web host what they recommend.
These may also help:
http://codex.wordpress.org/WordPress_Backups
https://www.google.com/search?q=how+to+backup+my+site
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Cristian Lavaque on "[Plugin: s2Member Framework (Member Roles, Capabilities, Membership, PayPal Members)] Signups get Level 0 not 1"
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